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<p class="p_c_title2 js_editor_click deep "> <a href="/product/7/" target="_blank"> <span>鐢叉哀鍩鸿仛涔欎簩閱囪鐢熺墿</span> </a> </p> <ul class="p_c_content deep-3"> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/84/" target="_blank"> <span>M-PEG-SCM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/85/" target="_blank"> <span>M-PEG-CM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/86/" target="_blank"> <span>M-PEG-SPA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/88/" target="_blank"> <span>M-PEG-SHA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/89/" target="_blank"> <span>M-PEG-HA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/90/" target="_blank"> 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href="/product/97/" target="_blank"> <span>M-PEG-VS</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/98/" target="_blank"> <span>M-PEG-SH</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/99/" target="_blank"> <span>M-PEG-ALD</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/100/" target="_blank"> <span>M-PEG-NH2HCl</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/101/" target="_blank"> <span>M-PEG-ACLT</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/102/" target="_blank"> <span>M-PEG-AZIDE</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/103/" target="_blank"> <span>M-PEG-ALKYNE</span> </a> </p> </li> <li class="p_c_item"> <p 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</p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/111/" target="_blank"> <span>M-PEG-PHOS</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/197/" target="_blank"> <span>M-PEG-GLU2</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/199/" target="_blank"> <span>M-PEG-BA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/200/" target="_blank"> <span>M-PEG-SBA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/201/" target="_blank"> <span>M-PEG-PA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/202/" target="_blank"> <span>M-PEG-GLU3</span> </a> </p> </li> </ul> </li> <li class="p_c_item"> <p class="p_c_title2 js_editor_click deep "> <a href="/product/9/" target="_blank"> <span>鍚屽畼鑳藉洟鍙屽彇浠EG琛嶇敓鐗?/span> </a> </p> <ul class="p_c_content deep-3"> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/21/" target="_blank"> <span>NH2HCl-PEG-NH2HCl</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/22/" target="_blank"> <span>ACLT-PEG-ACLT</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/23/" target="_blank"> <span>ALKYNE-PEG-ALKYNE,</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/24/" target="_blank"> <span>CM-PEG-CM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/25/" target="_blank"> <span>MAL-PEG-MAL</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/26/" target="_blank"> <span>SCM-PEG-SCM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/27/" target="_blank"> <span>HS-PEG-SH</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/28/" target="_blank"> <span>VS-PEG-VS</span> </a> </p> </li> </ul> </li> <li class="p_c_item"> <p class="p_c_title2 js_editor_click deep "> <a href="/product/10/" target="_blank"> <span>寮傚畼鑳藉洟鍙屽彇浠EG琛嶇敓鐗?/span> </a> </p> <ul class="p_c_content deep-3"> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/37/" target="_blank"> <span>ACLT-PEG-SCM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/38/" target="_blank"> <span>NH2HCl-PEG-CM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/39/" target="_blank"> <span>ALKYNE-PEG-MAL</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/40/" target="_blank"> <span>AZIDE-PEG-SCM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/41/" target="_blank"> <span>AZIDE-PEG-NH2TFA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/42/" target="_blank"> <span>BIOTIN-PEG-MAL</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/43/" target="_blank"> <span>BIOTIN-PEG-SCM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/44/" target="_blank"> <span>BIOTIN-PEG-SGA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/45/" target="_blank"> <span>FMOC-PEG-NH2TFA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/46/" target="_blank"> <span>FMOC-PEG-CM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/47/" target="_blank"> <span>FMOC-PEG-OH</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/48/" target="_blank"> <span>FMOC-PEG-SCM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/49/" target="_blank"> <span>HO-PEG-NH2HCl</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/50/" target="_blank"> <span>HO-PEG-CM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/51/" target="_blank"> <span>HO-PEG-SCM</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/52/" target="_blank"> <span>HO-PEG-PA</span> </a> </p> </li> <li class="p_c_item"> <p class="p_c_title3 js_editor_click deep "> <a href="/product/53/" target="_blank"> 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<p>鍦板潃锛氬寳浜競娴锋穩鍖鸿タ灏忓彛璺?6鍙蜂腑鍏虫潙涓滃崌绉戞妧鍥瑿-1妤间笁灞侟/p> </div></div> </div></div> </div> <input type="hidden" name="propJson" value='{"onpenAll_4":false,"href_5":{"type":"none","value":"","target":""},"href_7":{"type":"none","value":"","target":""},"aiSet_15":{"contentKeywords":"鐢熸垚涓€娈?{{鍏徃鍚嶇О}}${{琛屼笟}}鐨勫叕鍙哥畝浠嬪唴瀹?quot;,"type":1},"showImg_4":false,"aiSet_14":{"contentKeywords":"鐢熸垚涓€娈?{{鍏徃鍚嶇О}}${{琛屼笟}}鐨勫叕鍙哥畝浠嬪唴瀹?quot;,"type":1},"prompt_5":"","prompt_7":"","aiSet_7":{"contentKeywords":"鐢熸垚涓€娈?{{鍏徃鍚嶇О}}${{琛屼笟}}鐨勫叕鍙哥畝浠嬪唴瀹?quot;,"type":1},"dense_5":"","aiSet_5":{"contentKeywords":"鐢熸垚涓€娈?{{鍏徃鍚嶇О}}${{琛屼笟}}鐨勫叕鍙哥畝浠嬪唴瀹?quot;,"type":1},"dense_7":""}'/></div></div> <div id="content_box-1682664323660-1" class="d_gridCell_1 p_gridCell"><div id="c_product_detail_003_P_016-1654754902235"> <div class="e_container-2 s_layout"> <div class="cbox-2-0 p_item"><div class="e_magnifier-40 s_list" needjs="true"> <div class="magnifier thumb_bottom" id="magnifierWrapper"> <div class="magnifier-container">  <div class="images-cover"> <div class="image-item"> <img src="/npublic/img/s.png" lazy="https://omo-oss-image.thefastimg.com/portal-saas/new2023042821215034000/cms/image/6ed39bdc-c3c5-4003-9441-96233505acfe.png" alt="undefined" title="undefined" la="la"/> </div> </div>  <div class="image-bigger"> <div class="add-icon">+</div> </div>  <ul class="p_tabName"> <li class="js_nameItem p_nameItem active "> 浜у搧鎻忚堪 </li> <li class="js_nameItem p_nameItem "> 鍙傝€冩枃鐚 </li> </ul>  <ul class="p_tabContent">  <li class="p_contentItem active">  <div class="p_infoItem"> <div class="reset_style js-reset_style js-adapMobile "> <p>銆€銆€閿嚡绉戞妧鐢熶骇鍙斾竵姘х景姘ㄥ熀鑱氫箼浜岄唶鑳虹洂閰哥洂浜у搧涓惈鏈夌敱tBoc鍩哄洟淇濇姢鐨勮兒鍙婅兒鐨勭洂閰哥洂锛岄€氬父鐢ㄤ綔涓ょ涓嶅悓鍖栧鐗╄川鐨勪氦鑱斿墏鎴栭棿闅旂墿銆傛寮傚姛鑳絇EG琛嶇敓鐗╀腑鐨凱EG閮ㄥ垎鍙彁渚涙按婧舵€с€佺敓鐗╃浉瀹规€у強鏌旀€с€傛浜у搧涓撻棬搴旂敤浜庢姉浣撳伓鑱旇嵂鐗?ADC’s)鐨勫紑鍙戙€侟/p> <p>銆€銆€閿嚡绉戞妧鎻愪緵TBOC-PEG-NH2HCl鍒嗗瓙閲?000 Da,3500 Da, 5000 Da, 7500 Da鐨勪骇鍝?鍏嬪拰10鍏嬪寘瑁呫€侟/p> <p>銆€銆€閿嚡绉戞妧鎻愪緵鍒嗚鏈嶅姟锛岄渶瑕佹敹鍙栧垎瑁呰垂鐢紝濡傛灉鎮ㄩ渶瑕佸垎瑁呬负鍏朵粬瑙勬牸璇蜂笌鎴戜滑鑱旂郴銆侟/p> <p>銆€銆€閿嚡绉戞妧鍚屾椂鎻愪緵鍏朵粬鍒嗗瓙閲忕殑TBOC-PEG-NH2HCl琛嶇敓鐗╀骇鍝侊紝濡備綘闇€瑕佽涓庢垜鍙竤ales@jenkem.com鑱旂郴銆侟/p> <p>銆€銆€閿嚡绉戞妧鎻愪緵澶ф壒閲忕敓浜т骇鍝佸強GMP绾у埆浜у搧锛屽闇€鎶ヤ环璇蜂笌鎴戜滑鑱旂郴銆侟/p> <p style="box-sizing: border-box; margin: 0px 0px 20px; color: rgb(73, 73, 73); font-family: Cairo, Arial, Helvetica, sans-serif; font-size: 17px; font-weight: 600; background-color: rgb(255, 255, 255);"> </p> </div> </div> </li>  <li class="p_contentItem"> <p><font face="Arial">銆€銆€References:</font></p> <p><font face="Arial">銆€銆€1. Ai, F., et al., An upconversion nanoplatform with extracellular pH-driven tumor-targeting ability for improved photodynamic therapy, Nanoscale, 2018, 10(9), pp.4432-4441.</font></p> <p><font face="Arial">銆€銆€2. Huo, M., et al., Tumor-targeted delivery of sunitinib base enhances vaccine therapy for advanced melanoma by remodeling the tumor microenvironment, Journal of Controlled Release, 2017, V. 245, P. 81-94.</font></p> <p><font face="Arial">銆€銆€3. Gajbhiye, K.R., et al., Ascorbic acid tethered polymeric nanoparticles enable efficient brain delivery of galantamine: An in vitro-in vivo study, Scientific Reports, 2017, 7: 11086.</font></p> <p><font face="Arial">銆€銆€4. Li, Y., et al., A graphene quantum dot (GQD) nanosystem with redox-triggered cleavable PEG shell facilitating selective activation of the photosensitiser for photodynamic therapy, RSC Adv., 2016, 6, 6516-6522.</font></p> <p><font face="Arial">銆€銆€5. Zhang, X., et al., Multimodal Upconversion Nanoplatform with a Mitochondria-Targeted Property for Improved Photodynamic Therapy of Cancer Cells. Inorganic chemistry, 2016, 55(8):3872-80.</font></p> <p><font face="Arial">銆€銆€6. Zhao, Y., et al., Nanoparticle delivery of CDDO-Me remodels the tumor microenvironment and enhances vaccine therapy for melanoma, Biomaterials, 2015, V. 68, P. 54-66.</font></p> <p><font face="Arial">銆€銆€7. Li, H., et al., Dual MMP7-Proximity-Activated and Folate Receptor-Targeted Nanoparticles for siRNA Delivery, Biomacromolecules, 2015, 16 (1), p: 192–201.</font></p> <p><font face="Arial">銆€銆€8. Liu, J., et al., Integrin-targeted pH-responsive micelles for enhanced efficiency of anticancer treatment in vitro and in vivo, Nanoscale, 2015, 7, 4451-4460.</font></p> <p><font face="Arial">銆€銆€9. Baker, D.W., et al., Development of optical probes for in vivo imaging of polarized macrophages during foreign body reactions. Acta Biomaterialia, 2014, 10(7): p. 2945-2955.</font></p> <p><font face="Arial">銆€銆€10. Hsu, H.-J., et al., Poly(ethylene glycol) Corona Chain Length Controls End-Group-Dependent Cell Interactions of Dendron Micelles, Macromolecules, 2014, 47 (19), pp 6911–6918.</font></p> <p><font face="Arial">銆€銆€11. Miao, L., et al., Nanoparticles with Precise Ratiometric Co-Loading and Co-Delivery of Gemcitabine Monophosphate and Cisplatin for Treatment of Bladder Cancer, Adv. Funct. Mater., 2014, 24: 6601–6611.</font></p> <p><font face="Arial">銆€銆€12. Guo, S., et al., Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation. ACS nano, 2014, 8(5):4996-5009.</font></p> <p><font face="Arial">銆€銆€13. Zhou, J., et al., In vivo evaluation of medical device-associated inflammation using a macrophage-specific positron emission tomography (PET) imaging probe, Bioorganic & Medicinal Chemistry Letters, 2013, 23(7), p: 2044-2047.</font></p> <p><font face="Arial">銆€銆€14. Baker, D.W., The Pivotal Role Of Fibrocytes On Foreign Body Reactions, UTA, 2013.</font></p> <p><font face="Arial">銆€銆€15. Li, D., et al., A novel chlorin–PEG–folate conjugate with higher water solubility, lower cytotoxicity, better tumor targeting and photodynamic activity, Journal of Photochemistry and Photobiology B: Biology, 2013, 127, 5, p. 28-37.</font></p> <p><font face="Arial">銆€銆€16. Cao, P., et al., Improving Lanthanide Nanocrystal Colloidal Stability in Competitive Aqueous Buffer Solutions using Multivalent PEG-Phosphonate Ligands, Langmuir, 2012, 28(35), pp 12861–12870.</font></p> <p> 17. Han, Y., et al., Effective oral delivery of Exenatide-Zn2+ complex through distal ileum-targeted double layers nanocarriers modified with deoxycholic acid and glycocholic acid in diabetes therapy, Biomaterials, 2021, V. 275.</p> </li> </ul> </div></div> </div> <input type="hidden" name="propJson" 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