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p-id="1043"></path></svg> </a> </div> </div></div> </div><hr class="e_line-11 s_line" /><div class="e_container-12 s_layout"> <div class="cbox-12-0 p_item"><div class="e_richText-15 s_title clearfix myart"> <p> mRNA锛屼腑鏂囪瘧鍚?ldquo;淇′娇鏍哥硸鏍搁吀”锛屾槸鐢盌NA鐨勪竴鏉￠摼浣滀负妯℃澘杞綍鑰屾潵鐨勩€佹惡甯﹂仐浼犱俊鎭€佽兘鎸囧铔嬬櫧璐ㄥ悎鎴愮殑涓€绫诲崟閾炬牳绯栨牳閰搞€俶RNA鐨勫瓨鍦ㄩ鍏堢敱Jacques Monod鍜孎rançois Jacob鎻愬嚭锛屼箣鍚庣敱Jacob锛孲ydney Brenner鍜孧atthew Meselson浜?961骞村湪鍔犲窞鐞嗗伐瀛﹂櫌鍙戠幇銆?015骞翠互鏉ワ紝闅忕潃閫掗€佹妧鏈笌淇グ鎶€鏈殑鎴愮啛锛宮RNA浜т笟寮€濮嬪姞閫熷彂灞曪紝CureVac銆丅ioNTech鍜孧oderna绛変互mRNA鎶€鏈负鏍稿績鐨勭敓鐗╂妧鏈叕鍙镐篃娓愰湶澶磋銆?020骞寸殑鏂板啝鐤儏浣垮緱mRNA鐤嫍鍜岃嵂鐗╁彈鍒板叏鐞冭寖鍥村唴鐨勫箍娉涘叧娉紝骞跺甫鍔ㄤ簡mRNA棰嗗煙鐮旂┒鐨勮摤鍕冨彂灞曘€傛牴鎹甆ature鐩稿叧缁熻锛屾埅鑷?021骞?鏈堝簳锛屽叏鐞僲RNA鐤嫍鍜岃嵂鐗╁湪鐮旂绾垮叡180鏉★紝鍏朵腑缁濆ぇ閮ㄥ垎涓轰笌浼犳煋鐥呫€佺綍瑙佺梾鍜岃偪鐦ょ浉鍏崇殑鐮旂┒銆侟/p> <p>銆€銆€mRNA鍒嗗瓙閲忓ぇ銆佷翰姘存€у己锛屼絾鑷韩鐨勫崟閾剧粨鏋勬瀬涓嶇ǔ瀹氾紝鏄撹闄嶈В銆俶RNA鐨勬湁闄愬鍛戒娇缁嗚優鑳藉蹇€熸敼鍙樿泲鐧借川鍚堟垚浠ュ搷搴斿叾涓嶆柇鍙樺寲鐨勯渶姹傦紝鍗撮毦浠ユ弧瓒虫垚鑽€х殑瑕佹眰銆傚姞涓妋RNA鍒嗗瓙鏈韩鎼哄甫璐熺數鑽凤紝闅句互绌胯繃琛ㄩ潰鍚屼负璐熺數鑽风殑缁嗚優鑶滐紝鎵€浠ラ渶瑕佺壒娈婄殑淇グ鎴栧寘瑁归€掗€佺郴缁熸墠鑳藉疄鐜癿RNA鑽墿鐨勮優鍐呰〃杈撅紝鍥犳锛岄€掗€佹妧鏈槸mRNA鍏徃鐨勬牳蹇冧笓鍒╂妧鏈箣涓€銆侟/p> <p>銆€銆€鑴傝川绾崇背绮?Lipid 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